Publications
2021~2025
2016~2020
Selected out of 6 Publications (2022.06.07)
R. Kwag, J. Lee, D. Kim, H. Lee, M.Y. Yeom, J.W. Woo, Y. Cho, H.J. Kim, J. Kim, G. Keum, B. Jeon*, H. Choo*, Discovery of G protein-biased antagonists against 5-HT7R, J. Med. Chem. 2021, 64, 13766-13779
J. Lee, R. Kim, S. Lee, D. Kim, J. Woo, Y. Cho, H.J. Kim, J. Kim, B. Jeon, H. Choo*, Discovery of G Protein-Biased Ligands against 5-HT7R, J. Med. Chem. 2021, 64, 7453-7467
Y.J. Hwang, S.J. Hyeon, Y. Kim, S. Kim, M.Y. Lee, J. Kim, A.M. Londhe, L. Gotina, Y. Kim,, A.N. Pae, Y.S. Cho, J. Seong, H. Seo, Y.K. Kim, H. Choo*, H. Rhu*, S.-J. Min*, Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model, J. Enz. Inhib. Med. Chem. 2021, 36, 856-868
J. Lee, D. Avramets, B. Jeon*, H. Choo*, Modulation of Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor, Molecules, 2021, 26, 3348
Selected out of 26 Publications
Y. Kim, H. Kim, J. Lee, J.K. Lee, S.-J. Min, J. Seong, H. Rhim, J. Tae, H.J. Lee*, H. Choo*, Discovery of beta-Arresin Biased Ligands of 5-HT7R, J. Med. Chem. 2018, 61, 7218-7233
M.-H. Nam, M. Park, H. Park, Y. Kim, S. Yoon, V.S. Sawant, J.W. Choi, J.-H. Park, K.D. Park, S.-J. Min, C.J. Lee, H. Choo*, Indole-Substituted Benzothiazoles and Benzoxazoles as Selective and Reversible MAO-B Inhibitors for Treatment of Parkinson's Disease, ACS. Chem. Neurosci. 2017, 8, 1519-1529
Y. Kim, H. Park, J. Lee, J. Tae, H.J. Kim, S.-J. Min, H. Rhim, H. Choo*, 5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity, Eur. J. Med. Chem. 2016, 123, 180-19
2011~2015
Selected out of 31 Publications
X. Chen, H. Choo, X.-P. Huang, X. Yang, O. Stone, B.L. Roth*, J. Jin*, The First Structure-Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs, ACS Chem. Neurosci. 2015, 6, 476-484
Y. Kim, J. Kim, S. Kim, Y. Ki, S.H. Seo, J. Tae, M.K. Ko, H.-S. Jang, E.J. Lim, C. Song, Y. Cho, H.-Y. Koh, Y. Chong, I.H. Choo, G. Keum, S.-J. Min, H. Choo*, Novel thienopyrimidinones as mGluR1 antagonists, Eur. J. Med. Chem. 2014, 85, 629-637
~2010
53 Publications more